Alfred Health is a leader in health care delivery, improvement, research and education. We are the main provider of health services to people living in the inner southeast suburbs of Melbourne, from ambulatory, to inpatient and home and community based services.
Fixed Term : 12 months
Full Time : 76 hours per fortnight
Location: The Alfred Centre, 99 Commercial Road
An exciting opportunity exists for a Research Assistant to join the Australian Centre for Blood Diseases within Central Clinical School. The incumbent will join the cancer epigenetics Laboratory investigating aberrant epigenetic pathways in haematological malignancies. The project involves investigation of the precise chromatin events that sustain the growth of blood cancers and the determinants of therapy response and resistance for compounds in clinical development.
The laboratory is focused on discovering novel epigenetic regulators as potential therapeutic targets for aggressive blood cancers. The projects would also involve more fundamental investigation of gene regulatory mechanisms in both normal and malignant contexts. The lab utilises a wide variety of cutting edge genomic/chromatin assays as well as CRISPR screens, functional assays and in vivo mousemodels.
The position requires a research scientist with experience in cell biology, molecular biology and biochemical techniques to assist in the development of novel agents for targeting aggressive blood cancers. The successful candidate should hold a BSc (Honours) or equivalent and have a background in experimental haematology and/or cancer biology. The person will be expected to conduct rigorous, valid and ethical research both independently and as part of the research team, and to have excellent organizational and time management skills. The position suits someone who intends to potentially undertake a PhD in the future.
Mammalian cell culture
qRT-PCR, PCR, cloning
Western blotting/protein biochemistry
ChIP, and ATAC-seq, desirable but not essential.
Knowledge of NGS technology, desirable but not essential.
High quality written and oral communication skills
High level of interpersonal skills
Flexibility and ability to develop new skills
There will be many opportunities to grow as a scientist and learn about cutting edge methods in the molecular biology and cancer research field.
Alfred Health is an equal opportunity employer and is committed to attracting and retaining a diverse workforce that reflects the community we serve. Applications from Aboriginal and Torres Strait Islanders are encouraged.